Dr. Nicholas Mantis Awarded $9 Million Contract to Aid in Diagnosis, Prevention and Treatment of Lyme Disease

Dr. Nicholas Mantis, of Wadsworth Center's Division of Infectious Diseases, was awarded a five-year, $9 million contract by the National Institute of Allergy and Infectious Diseases (NIAID) to study human antibody responses to the Lyme disease pathogen, Borrelia burgdorferi.  

A New Game Plan - Wadsworth Center’s Dr. Jon Paczkowski Awarded $1.8 Million NIH Grant to Study Regulation of Virulence Factors

​Current antibiotics work by interfering with bacterial growth, which is a fine game plan… until it stops working. More and more, bacteria are finding ways around this approach, resulting in a huge antibiotic resistance problem. Dr. Jon Paczkowski may just have come up with a new defensive strategy and recently received a five-year grant from the National Institutes of Health to investigate.

Radical Solutions: Diagnosing and Even Predicting COVID-caused MIS-C

As we’ve seen repeatedly during the pandemic, it isn’t always easy to get our hands on everything we need, hmmm, cue the toilet paper, especially new things. This reality translates to addressing patients who have COVID today. By using tools we already have in labs across the country, we can capitalize on the technology, instruments and the know how to use them by using them in new ways.

Wadsworth Center Scientists Featured in Association of Public Health Laboratories' Lab Matters

Dr. St. George is quoted in the feature article beginning on page 5 and our own Infectious Disease Fellow Nora Cleary is featured on pg 19. Nora has been selected for the Edith Hsiung Memorial prize for her abstract/presentation on Hep A whole genome sequencing.  This is one of the two top travel awards from the American Society for Microbiology for a student, fellow, or technologist, presenting their work at the annual, international Clinical Virology Symposium, to be held this year in West Palm Beach.

Under Construction…Permanently. 25 Years of Wadsworth Center’s Clinical Laboratory Information Management System (CLIMS)

Having spent a lot of time in our homes recently, most of us are probably contemplating a dream renovation. If that project requires several professionals - plumbers, electricians, carpenters, etc., we might have second thoughts.

Wadsworth Center’s Laboratory of Organic Analytical Chemistry Continues to Test Vaping Fluids Suspected of Causing Illness From New York State

In 2019, cases of a mysterious illness related to vaping, formally referred to as “e-cigarette or vaping product use-associated lung injury” (EVALI), were identified across the United States.  A significant number of cases affected young New Yorkers.  In association with NY Regional Poison Control Centers and medical facilities from around the state, Wadsworth Center’s Laboratory of Organic Analytical Chemistry analyzed vape fluid samples from suspected cases for cannabinoids, pesticides, synthetic cannabinoids, opioids, illicit drugs, an

Wadsworth Center Leads the Way in Number of NYS COVID Variants Sequenced

SARS-CoV-2, like all viruses, is constantly creating new variants through mutation of its RNA genome. Most mutations are of little or no consequence. However, every once in a while, a new mutation can increase transmissibility, increase disease severity, cause the virus to escape the body’s immune response, or do any combination of these.

Deciphering the sleep/wake cycle of ribosomes in mycobacteria

Infections with Mycobacterium tuberculosis (Mtb),  the etiological agent of tuberculosis (TB) in humans, are difficult to eradicate with antibiotics: a 6-month long multidrug regimen is necessary for the treatment of TB.  The drug recalcitrance of TB infections has been associated with a specialized subpopulation of Mtb cells, that do not replicate or are very slow growing and whose metabolism is significantly decreased.